ULTRASONIC SYNTHESIS, MOLECULAR STRUCTURE AND MECHANISTIC STUDY OF 1,3-DIPOLAR CYCLOADDITION REACTION OF 1-ALKYNYLPYRIDINIUM-3-OLATE AND ACETYLENE DERIVATIVES

Regioselectively, ethyl propiolate reacted with 1-(propergyl)-pyridinium-3-olate to give two regioisomers; ethyl 4-oxo-8-(prop-2-ynyl)-8-aza-bicyclo(3.2.1)octa-2,6-diene-6-carboxylate 4, ethyl 2-oxo-8-(prop-2-ynyl)-8-aza-bicyclo(3.2.1)octa-3,6-diene-6-carboxylate 5 as well as ethyl 2,6-dihydro-6-(prop-2-ynyl)furo(2,3-c)pyridine-3-carboxylate 6.The

The [Paris polyphylla Smith var.Yunnanensis (Franch.) Hand.- Mazz] (The following is denoted Ring Toss by P.polyphylla) contains various chemical components such as steroidal saponins, flavonoids, polysaccharides, amino acids, etc.It is a traditional Chinese medicinal herb with important medicinal value.So far, the pharmacological research on P.pol

BackgroundSystemic lupus erythematosus is a chronic, multisystem, inflammatory disease of autoimmune etiology occurring predominantly in women.A major hurdle to the diagnosis, treatment, and therapeutic advancement of this disease is its heterogeneous nature, which presents as a wide range of symptoms such as fatigue, fever, musculoskeletal involve